Floating disk for separating blood components

摘要

A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.

主权项

1. An article for ensuring separation of components of a physiological fluid comprising a tubular chamber forming a cavity for receiving said physiological fluid, said tubular chamber having a separating element therein, said separating element being configured to float in said physiological fluid and to assume a position in said tubular chamber according to respective densities of separated components of said physiological fluid, said separating element comprising a positioning part configured to float in a first, lighter component of said physiological fluid at an interface with plasma, and a separating part spaced from said positioning part by a predetermined distance and configured to float in a second, denser component and to extend at least partially across said tubular chamber to physically separate said first component from said second component, wherein the mass of said positioning part is at least about 65% of the total mass of the separating element.