发明名称 |
PROCESS FOR METABOLIC CONTROL AND HIGH SOLUTE CLEARANCE AND SOLUTIONS FOR USE THEREIN |
摘要 |
<p>The present disclosure describes novel standardized citrate replacement fluid solutions and a standardized dialysate solution for use with CRRT methods. The standardized citrate replacement fluid solutions and standardized dialysate solutions do not require modification based on the clinical status of the individual patients. The use of the standardized solutions described herein offers significant advantages over the prior art solutions used in CRRT. The present disclosure describes superior metabolic and electrolyte control and significantly increased dialyzer patency in: (a) 24 intensive care unit (ICU) patients with ARF using a 0.67% trisodium citrate replacement fluid solution, and (b) 32 ICU patients with ARF using a 0.5% trisodium citrate replacement fluid solution. Both groups were treated with Bicarbonate-25 dialysate and achieved effluent rates of 35 mL/kg/hr.</p> |
申请公布号 |
PT1948205(E) |
申请公布日期 |
2015.10.16 |
申请号 |
PT20060837587T |
申请日期 |
2006.11.14 |
申请人 |
THE UAB RESEARCH FOUNDATION |
发明人 |
ASHITA TOLWANI;RAJESH SPEE;BRENDA STOFAN |
分类号 |
A61K33/00;A61K31/194 |
主分类号 |
A61K33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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