CATIONIC ANTIMICROBIAL PEPTIDES

摘要

A method for treating an infection comprises administering a peptide in synergistic combination with an antibiotic, wherein the peptide comprises an amino acid sequence with a formula selected from the group consisting of: (a) B n1 - Z; (b) B n1 - Z - B n2; and (c) Z - B n1 wherein B is a basic amino acid residue; n1 and n2 are 1 to 6; and Z is a sequence of from about 7 to about 24 amino acid residues, said sequence having an average hydrophobicity value of at least 0.3 on the Liu-Deber scale.