发明名称 BISPECIFIC HER2 ANTIBODIES
摘要 The present invention relates to anti-HER2 binding molecules (e.g., antibodies and antigen binding fragments thereof), derived HER2-binding molecules (e.g., bispecific anti-HER2 antibodies), and antibody-drug conjugates (ADC) that bind the extracellular domain of the HER2 receptor. Also provided are pharmaceutical formulation comprising the disclosed compositions and method for the treating diseases associated with HER2-mediated signal transduction.
申请公布号 CA2943299(A1) 申请公布日期 2015.10.15
申请号 CA20152943299 申请日期 2015.04.10
申请人 MEDIMMUNE, LLC 发明人 LI, JOHN;DIMASI, NAZZARENO;COATS, STEVEN;DAMSCHRODER, MELISSA;GAO, CHANGSHOU;RAINEY, GODFREY;GAO, CUIHUA;TOADER, DORIN;GINGIPALLI, LAKSHMAIAH;WANG, FENGJIANG;FLEMING, RYAN;BEZABEH, BINYAM;YUAN, ANDY QINGAN;KASTURIRANGAN, SRINATH
分类号 A61K39/395;A61K45/06;C07K16/40 主分类号 A61K39/395
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