METHOD FOR PREPARING CHIRAL ALCOHOLS FROM RACEMIC OR MESO ALCOHOLS

摘要

Disclosed is a method for producing a chiral alcohol compound. According to the present invention, a stereoselective reaction between a racemic alcohol compound or a mesoalcohol compound and a silylation agent can be performed in the presence of a chiral catalyst compound to produce a chiral alcohol compound. In this case, a compound obtained by derivatizing oligo ethylene glycol including a hydroxy functional group of a binol derivative, which is an acid portion, and an oligo ethylene glycol functional group, which is an alkali portion, can be used as the chrial catalyst compound.