发明名称 |
MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS |
摘要 |
Disclosed are modified thymine bases that provide enhanced base-pairing affinity for adenine or 2,6-diaminopurine bases in polynucleotide hybridization complexes. Also disclosed are polynucleotide oligomers, polynucleotide hybridization complexes that comprise such modified thymine bases. Also disclosed are various methods of use. For example, in some embodiments, modified polynucleotide oligomers disclosed herein can be used as primers and probes for nucleic acid amplification and/or detection. |
申请公布号 |
WO2015153496(A1) |
申请公布日期 |
2015.10.08 |
申请号 |
WO2015US23403 |
申请日期 |
2015.03.30 |
申请人 |
CEPHEID |
发明人 |
GALL, ALEXANDER A.;LOKHOV, SERGEY G.;PODYMINOGIN, MIKHAIL;VIAZOVKINA, EKATERINA V.;LUND, KEVIN PATRICK |
分类号 |
C07H19/06;C07H21/00;C12Q1/68 |
主分类号 |
C07H19/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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