LIQUID PHARMACEUTICAL COMPOSITION OF CONJUGATED ERYTHROPOIETIN

摘要

Abstract The present invention relates to a liquid pharmaceutical composition comprising a conjugated erythropoietin, buffer, sugar, tonicity modifier and amino acid as an aggregation inhibitor. More preferably the present invention provides a stable pharmaceutical composition which encompasses conjugated erythropoietin comprising acetate buffer, sucrose, arginine and sodium chloride and maintained at a pH of about 4.9 to 5.3.