发明名称 Process for producing amino acids
摘要 The present invention provides: a process for producing an amino acid which comprises adding crystals of the amino acid having an average particle size of 1 to 120 μm to a medium so that the concentration of the crystals of the amino acid becomes 0.5 g/l or more, culturing a microorganism having the ability to produce the amino acid in the medium, allowing crystals of the amino acid to form and accumulate in the medium, and recovering the crystals of the amino acid from the culture; and a process for producing an amino acid which comprises adding crystals of the amino acid to a medium so that the total surface area of the crystals of the amino acid in the medium becomes 0.02 m2/l, culturing a microorganism having the ability to produce the amino acid in the medium, allowing crystals of the amino acid to form and accumulate in the medium, and recovering the crystals of the amino acid from the culture.
申请公布号 USRE45723(E1) 申请公布日期 2015.10.06
申请号 US201414329255 申请日期 2014.07.11
申请人 KYOWA HAKKO BIO CO., LTD. 发明人 Shimose Tsuyoshi;Ohashi Ryou;Fujinaga Katsumi
分类号 C12P13/22;C12P13/04;C12P13/06;C12P13/14;C12P13/08 主分类号 C12P13/22
代理机构 Fitzpatrick, Cella, Harper & Scinto 代理人 Fitzpatrick, Cella, Harper & Scinto
主权项 1. A process for producing an amino acid, which comprises: culturing a microorganism having an ability to produce the amino acid in a medium, adding crystals of the amino acid having an average particle size of 1 to 1207 to 50 μm to athe medium at some time after the amino acid concentration in the medium reaches the saturation solubility and before crystals of the amino acid deposit in the medium so that the concentration of the crystals of the amino acid becomes 0.5 g/l or more, culturing athe microorganism having the ability to produce the amino acid in the medium, allowing the crystals of the amino acid to formgrow to crystals of the amino acid having an average particle size of 30 μm or more and accumulate in the medium, and recovering the crystals of the amino acid from the culture by separating the microorganism producing the amino acid and the accumulated crystals of the amino acid based on the difference in particle size or specific gravity between them.
地址 Tokyo JP
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