发明名称 TOLL-LIKE RECEPTOR (TLR) STIMULATION FOR OCULAR ANGIOGENESIS AND MACULAR DEGENERATION
摘要 Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of stimulators of the TLR3 or TLR7 receptors, Trif or of IL-10 or IL-12 inhibits ocular angiogenesis. Furthermore, all siRNAs (both targeted and non-targeted) can inhibit ocular angiogenesis.
申请公布号 WO2007133800(A3) 申请公布日期 2008.04.24
申请号 WO2007US11718 申请日期 2007.05.15
申请人 UNIVERSITY OF KENTUCKY;AMBATI, JAYAKRISHNA 发明人 AMBATI, JAYAKRISHNA
分类号 A01N43/26;A61K31/385 主分类号 A01N43/26
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