| 摘要 |
Disclosed are: a novel aminoglycoside antibiotic which has an excellent anti-bacterial activity against an infection-inducing bacterium, particularly MRSA, and also has low renal toxicity; and a process for production of the antibiotic. More specifically, disclosed are: a compound represented by the formula (Ia) or a pharmacologically acceptable salt or solvate thereof, or a diastereomeric mixture of the compound, the salt or the solvate; an antibacterial agent comprising the compound, the salt, the solvate or the diastereomeric mixture; and a process for production of the compound. [Chemical formula 1] (Ia) |
| 申请人 |
MEIJI SEIKA KAISHA, LTD.;MICROBIAL CHEMISTRY RESEARCH FOUNDATION;KOBAYASHI, YOSHIHIKO;AKIYAMA, YOSHIHISA;MURAKAMI, TAKESHI;MINOWA, NOBUTO;TSUSHIMA, MASAKI;HIRAIWA, YUKIKO;MURAKAMI, SHOICHI;ABE, MITSUHIRO;SASAKI, KAZUSHIGE;HOSHIKO, SHIGERU;MIYAKE, TOSHIAKI;TAKAHASHI, YOSHIAKI;IKEDA, DAISHIRO |
发明人 |
KOBAYASHI, YOSHIHIKO;AKIYAMA, YOSHIHISA;MURAKAMI, TAKESHI;MINOWA, NOBUTO;TSUSHIMA, MASAKI;HIRAIWA, YUKIKO;MURAKAMI, SHOICHI;ABE, MITSUHIRO;SASAKI, KAZUSHIGE;HOSHIKO, SHIGERU;MIYAKE, TOSHIAKI;TAKAHASHI, YOSHIAKI;IKEDA, DAISHIRO |
