MODULATION OF THE IMMUNE SYSTEM BY INOSITOL PHOSPHOLIPIDS

摘要

The invention relates to the field of immunology. More specifically, it relates to compositions and uses thereof to suppress the immune system, among other by interference with antigen-presenting molecules and T-cell activation. Provided is a composition for the prevention or treatment of a condition wherein suppression of T cell activation is desirable, comprising as an active ingredient an inositol phospholipid or a pharmaceutically acceptable salt thereof . Said condition can be an auto-immune disease, allergic disorder or chronic inflammatory disease, for example asthma, diabetes Type I, rheumatoid arthritis (RA) or inflammatory bowel disease (IBD) . Also provided is a food item or food supplement having immunomodulating properties, comprising an effective amount of an inositol phospholipid.