发明名称 |
DRY POWDER PREPARATIONS FOR PRE-METERED DPI |
摘要 |
<p>A dry powder medicament preparation is disclosed. Also methods of forming and loading metered doses of the preparation into dose containers intended for insertion into a dry powder inhaler are disclosed. The preparation is adapted for a dose forming process, which may be based on volumetric filling or electro-dynamic deposition of the powder particles, such that a metered dose of the preparation is characterized by having at least one load of held-together particles joined in a macrostructure of predefined dimensions and presenting an intended mechanical strength. The pharmacologically active ingredient presents at least 50% by mass of particles in a typical aerodynamic diameter range from 1 to 5 mum. Furthermore, a dose thus formed is then loaded into a high barrier container.</p> |
申请公布号 |
EP1732515(A1) |
申请公布日期 |
2006.12.20 |
申请号 |
EP20050722259 |
申请日期 |
2005.03.23 |
申请人 |
MEDERIO AG |
发明人 |
NILSSON, THOMAS;FRIBERG, CLAES;KAX, LARS;NIEMI, ALF;CALANDER, SVEN |
分类号 |
A61K9/14;A61J3/00;A61K9/00;A61K9/72;A61M;A61M15/00;A61M16/00;A62B7/00;B65B1/36 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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