MODIFIED ACYL TRANSFERASES FOR THE PRODUCTION OF DIFFERENT LACTAM ANTIBIOTICS
摘要
<p>The present invention relates to polypeptides with acyl-CoA:isopenicillin N acyltransferase (AT) activity that are variants of a model polypeptide with AT activity, the variants having a modified specificity for the side chain and/or a modified specificity for the beta-lactam nucleus.</p>
申请公布号
WO2006089951(A1)
申请公布日期
2006.08.31
申请号
WO2006EP60267
申请日期
2006.02.24
申请人
DSM IP ASSETS B.V.;LAAN, VAN DER, JAN, METSKE;SUTHERLAND, JOHN, DAVID;HENSGENS, CHARLES, MARIA, HUBERT;DIJKSTRA, BAUKE, WIEPKE