DIHYDROTHIENOQUINOLINE DERIVATIVE AND CELL ADHESION INHIBITOR CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a compound useful as a cell adhesion inhibitor. SOLUTION: A dihydrothienoquinoline derivative is represented by general formula (I) äwherein R1is represented by formula (II) or formula (III) (wherein R3or R4is a 1-6C unsaturated or saturated lower alkyl group, a 6-12C unsaturated or saturated aryl group, a 3-11C unsaturated or saturated heteroaryl group, a 7-14C unsaturated or saturated aralkyl group or a 4-13C unsaturated or saturated heteroarylalkyl group); R2is a hydrogen atom, a 1-6C unsaturated or saturated lower alkyl group, a hydroxy group, a 1-6C unsaturated or saturated alkoxy group, a 2-11C unsaturated or saturated acyloxy group, a carboxy group which may be esterified or amidated, an unsaturated or saturated amino group, a nitro group, a cyano group or a halogen atom; X is a group represented by the formula: CONR5R6}. The cell adhesion inhibitor contains the derivative. COPYRIGHT: (C)2006,JPO&NCIPI