<p>Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed</p>
申请公布号
WO2006063154(A1)
申请公布日期
2006.06.15
申请号
WO2005US44451
申请日期
2005.12.07
申请人
PROTEOLIX, INC.;LEWIS, EVAN, R.;HO, MARK NGUYEN;FONESCA, FABIANA, N.
发明人
LEWIS, EVAN, R.;HO, MARK NGUYEN;FONESCA, FABIANA, N.