The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies that specifically recognize and bind to specific epitopes from a range of ?-amyloid proteins. The antibodies of the present invention are particularly useful for the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system, particularly associated with amyloid-beta-related pathological abnormalities/changes in the tissues of the visual system.
申请公布号
CA2701790(A1)
申请公布日期
2009.04.16
申请号
CA20082701790
申请日期
2008.10.03
申请人
AC IMMUNE S.A.;GENENTECH, INC.
发明人
PFEIFER, ANDREA;MUHS, ANDREAS;WATTS, RYAN;PIHLGREN, MARIA