发明名称 |
HIGH EFFICIENCY TISSUE-SPECIFIC COMPOUND DELIVERY SYSTEM USING STREPTAVADIN-PROTEIN A FUSION PROTEIN |
摘要 |
The present invention relates to methods and compositions that can be employed to introduce toxins and nucleic acids into the cytoplasm or nucleus of a eukaryotic cell, particularly a cell of a higher vertebrate. The invention particularly concerns the use of a fusion protein of streptavidin and protein A sequences to form a non-covalent complex of a toxin or nucleic acid and an antibody.
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申请公布号 |
US2009098148(A1) |
申请公布日期 |
2009.04.16 |
申请号 |
US20080335010 |
申请日期 |
2008.12.15 |
申请人 |
NEW YORK UNIVERSITY |
发明人 |
MERUELO DANIEL;OHNO KOUICHI;LEVIN BRANDI A. |
分类号 |
A61K39/395;C12N15/02;A61K38/00;A61K47/48;A61K48/00;C07K16/18;C07K16/28;C07K19/00;C12N9/96;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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