METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS

摘要

Methods and compositions for modulating angiogenesis in a subject are provided. Aspects of the invention include administering an effective amount of a TXR1 modulatory agent, e.g., a TXR1 agonist or antagonist, to a subject. Embodiments of the methods find use in a variety of different applications, including the inhibition of tumor growth and the treatment of disease conditions characterized by tumor presence.