APROCESS FOR THE PREPARATION OF COPOLYMER - 1 (COP-I), COMPOSED OF L-ALANINE, L-LYSINE, L-GLUTAMIC ACID AND L-TYROSINE-DRUG FOR THE TREATMENT OF MULTIPLE SCLEROSIS

摘要

A process for the synthesis of copolymer-1 composed of L-alanine, LHysine, L-glutamic acid and L-tyrosine for the treatment of multiple sclerosis.The molecular weight of copolymer-1 is between 8-19 KDa. Process is initiated by supported dialkyl amine. The copolymer-1 of the invention has acid content of less than 1%.