发明名称 Tartrate salts of quinazoline based EGFR inhibitors containing a zinc binding moiety
摘要 The present invention relates to tartrate salts of quinazoline containing zinc-binding moiety based derivatives of Formula II, below. These compounds are inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and may further act as HDAC inhibitors. The invention further relates to the use of these tartrate salts in the treatment of EGFR-TK related diseases and disorders such as cancer.
申请公布号 US7846938(B2) 申请公布日期 2010.12.07
申请号 US20080207833 申请日期 2008.09.10
申请人 CURIS, INC. 发明人 CAI XIONG;QIAN CHANGGENG;ZHAI HAIXIAO
分类号 A61K31/517 主分类号 A61K31/517
代理机构 代理人
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