发明名称 |
ANTIBODY DIRECTED AGAINST PCRV |
摘要 |
Provided is an effective means for therapy of infection, particularly infection with Pseudomonas aeruginosa. Provided are a monoclonal antibody against PcrV or a part thereof, and a pharmaceutical composition containing the same as an active ingredient. Concretely, monoclonal antibody of the present invention has excellent inhibiting activity on cytotoxicity with respect to a target cell of Pseudomonas aeruginosa. Also, the monoclonal antibody of the present invention has high affinity with PcrV.
|
申请公布号 |
EP2248826(A1) |
申请公布日期 |
2010.11.10 |
申请号 |
EP20090701235 |
申请日期 |
2009.01.08 |
申请人 |
SHIONOGI&CO., LTD. |
发明人 |
NUMATA, YOSHITO;YAMANO, YOSHINORI;SATO, TAKAFUMI;TSUJI, TOSHINAGA |
分类号 |
C07K16/12;A61K39/395;A61P31/04;C12N5/10;C12N15/09;C12P21/08 |
主分类号 |
C07K16/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|