发明名称 |
DETERMINING mRNA LEVEL REDUCTION IN GENES ITGA9, HYAL1 AND HYAL2 AS METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR ITS REALISATION |
摘要 |
FIELD: medicine. ^ SUBSTANCE: invention is claimed as application of mRNA level of genes 1TGA9, HYAL1 and HYAL2 as markers for diagnostics of epidermoid lung cancer (ELC) and lung adenocarcinoma (LA). Decreased mRNA level of said genes in supposedly affected with cancer human tissue in comparison with its level in healthy tissue serves as diagnostic marker of non-small cell lung cancer. ^ EFFECT: invention allows to diagnose non-small cell lung cancer of LA and ELC type with high reliability, including the earliest clinical stage of tumour disease. ^ 3 tbl, 7 ex, 1 dwg |
申请公布号 |
RU2403575(C2) |
申请公布日期 |
2010.11.10 |
申请号 |
RU20080137430 |
申请日期 |
2008.09.18 |
申请人 |
FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT ONKOLOGII IMENI N.N. PETROVA PO VYSOKOTEKHNOLOGICHNOJ MEDITSINSKOJ POMOSHCHI" |
发明人 |
SENCHENKO VERA NIKOLAEVNA;ANEDCHENKO EKATERINA ANATOL'EVNA;KONDRAT'EVA TAT'JANA TIKHONOVNA;SAKHAROVA OL'GA VIKTOROVNA;IMJANITOV EVGENIJ NAUMOVICH;FREJDLIN IRINA SOLOMONOVNA |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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