Motion control systems and methods for biosensor scanning

摘要

Motion control system and method for biosensor scanning that include inputting to a multi-axis motion controller move commands associated with the scan path as defined by multiple axes. The multiple axes including an x-baseline coordinate x0, a y-baseline coordinate y0, an x-direction oscillation amplitude x1, a y-direction oscillation amplitude y1, an oscillation frequency f and a phase φ. The multi-axis motion controller outputs digital commanded positions for each of the multiple axes. A post-processor receives the commanded positions and generates parameterized commanded positions x and y that each include a baseline motion component and an oscillating motion component. The parameterized commanded positions cause the scanning optical system to deflect the light beam to scan the beam spot over the scan path to scan the biosensor.

主权项

1. A method of defining a scan path using a scanning optical system to scan a beam spot formed by a light beam over one or more biosensors supported by a microplate, comprising:
inputting to a multi-axis motion controller move commands associated with the scan path as defined by multiple axis comprising an x-baseline coordinate x0, a y-baseline coordinate y0, an x-direction oscillation amplitude x1, a y-direction oscillation amplitude y1, an oscillation frequency f and a phase φ; outputting from the multi-axis motion controller commanded positions for each of the multiple axes; receiving the commanded positions with a post-processor and generating therein parameterized commanded positions x and y defined the following equations where t is time and OSC is an oscillatory function:
x=x0+x1·OSC(2π·f·t+φ) and y=y0+y1·OSC(2π·f·t+φ); and inputting the parameterized commanded positions x and y to a scanning optical system to cause the scanning optical system to deflect the light beam to scan the beam spot over the scan path.