Method and use for measurement of nk cell activity

摘要

Disclosed is a method of measuring NK cell activity, comprising: stimulating NK cells in a whole blood sample thereby artificially activating the NK cells to generate NK cell-secreting cytokines; and measuring an amount of the NK cell-secreting cytokines in the whole blood sample. Use of at least one stimulating cytokine, lipopolysaccharide (LPS) or polyinosinic:polycytidylic acid (poly I:C) in the manufacture of a kit for measuring NK cell activity, wherein the at least one stimulating cytokine, lipopolysaccharide (LPS) or polyinosinic:polycytidylic acid (poly I:C) is provided for stimulating NK cells in a whole blood sample and thereby artificially activating the NK cells to generate NK cell-secreting cytokines, and wherein an amount of the NK cell-secreting cytokines in the whole blood sample is used to measure NK cell activity .