发明名称 |
COMPOSITIONS AND METHODS FOR REDUCING OXIDATIVE DAMAGE |
摘要 |
Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject. |
申请公布号 |
EP2922919(A1) |
申请公布日期 |
2015.09.30 |
申请号 |
EP20130857463 |
申请日期 |
2013.11.21 |
申请人 |
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. |
发明人 |
TEZEL, TONGALP H.;GOBIN, ANDREA S.;O'TOOLE, MARTIN G. |
分类号 |
C08L71/00;C08J3/20;C08K5/00;C08L1/02;C08L71/02 |
主分类号 |
C08L71/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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