发明名称 |
CARDIOMYOCYTE SORTING METHOD |
摘要 |
An objective of the present invention is to provide a new cardiomyocyte sorting method. A further objective of the present invention is to provide a method for manufacturing high-purity cardiomyocytes, and a kit for said method. The present invention achieves the above by providing a cardiomyocyte sorting method that includes a step in which miRNA-responsive mRNA is introduced into groups of cells, said miRNA-responsive mRNA comprising a sequence containing (i) a nucleic acid that is specifically recognized by miRNA specifically expressed in cardiomyocytes and (ii) a nucleic acid that corresponds to the coding region of a gene, wherein the nucleic acid sequence from (i) is used to control the translation of the nucleic acid from (ii), which corresponds to the coding region of a gene, into a protein. |
申请公布号 |
WO2015141827(A1) |
申请公布日期 |
2015.09.24 |
申请号 |
WO2015JP58466 |
申请日期 |
2015.03.20 |
申请人 |
KYOTO UNIVERSITY |
发明人 |
YOSHIDA, YOSHINORI;SAITO, HIROHIDE;MIKI, KENJI;ENDO, KEI;TAKAHASHI, SEIYA |
分类号 |
C12N15/09;C12Q1/04;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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