Substituted (R)-3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-enecarboxylic acid (variants) and ester thereof, method for producing and using same

摘要

The present invention relates to novel chemical compounds of general formula 1 which are intermediate products of the synthesis of androgen receptor inhibitors that are of interest as anticancer preparations. The subject matter of the invention also includes methods for producing novel compounds of general formula 1.1 which are androgen receptor inhibitors. Claimed are substituted 3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-enecarboxylic acids or esters of general formula 1 or 1.1, or stereoisomers thereof, wherein in formula 1 R