PARTICULATE TISSUE GRAFT WITH COMPONENTS OF DIFFERING DENSITY AND METHODS OF MAKING AND USING THE SAME

摘要

Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.

主权项

1. A composition of bioresorbable particulate matter comprising:
a first plurality of bioresorbable particles having a first density and a first rate of resorption on implantation at a site in a patient and a second plurality of particles having a second density and a second rate of resorption on implantation at the site in a patient, wherein the second density is at least 150% of the first density, the second rate of resorption is in the range of about 1 to about 10 times the first rate of resorption, and said first plurality and second plurality of bioresorbable particles promote tissue restoration and repair when implanted at a tissue site in a mammalian patient.