Method for protecting a retinal neuronal cell

摘要

A method of protecting a retinal neuronal cell by administering an effective amount of a prostaglandin F2α derivative to a patient. A method of preventing or treating an eye disease associated with retinal neuronal cell damage by administering a therapeutically effective amount of a prostaglandin F2α derivative to a patient.

主权项

1. A method for treating an eye disease selected from the group consisting of abnormal visual field, retinal vascular occlusion, diabetic retinopathy, ischemic optic neuropathy, macular degeneration, retinitis pigmentosa and Leber's disease, the method comprising administering to a patient in need thereof, wherein the patient does not have glaucoma, a therapeutically effective amount of a 15,15-difluoroprostaglandin F2α derivative is a compound represented by the following formula (1) or a salt thereof:wherein R represents a hydroxyalkyl group, a formyl group, a carboxy group, an isopropoxycarbonyl group, an alkoxycarbonyl group, an aryloxycarbonyl group, an aminocarbonyl group, an alkylaminocarbonyl group or an arylaminocarbonyl group, and when R is an aryloxycarbonyl group or an arylaminocarbonyl group, the aryl moiety thereof may have a substituent.