发明名称 ANTIBODIES AGAINST A PROLIFERATING INDUCING LIGAND (APRIL)
摘要 PROBLEM TO BE SOLVED: To provide compositions of anti-APRIL specific antibodies and methods to use such antibodies in modulating the biological activity APRIL, particularly in inflammatory diseases, inhibition of cell proliferation and cancer.SOLUTION: The present invention relates to a binding compound which binds to human APRIL, the compound binding to APRIL of the amino acid sequence IRSMPSHPDRA or VSREGQGRQ.
申请公布号 JP2015164956(A) 申请公布日期 2015.09.17
申请号 JP20150117304 申请日期 2015.06.10
申请人 BIONOVION HOLDING BV 发明人 JAN PAUL MEDEMA;HANS VAN EENENNAAM;MARCO GUADAGNOLI;FIONA CLARE KIMBERLEY;UYEN TRUONG PHAN
分类号 C07K16/18;A61K39/395;A61P29/00;A61P35/00;A61P37/02;A61P37/04;A61P37/06;A61P43/00 主分类号 C07K16/18
代理机构 代理人
主权项
地址