发明名称 |
ANTIBODIES AGAINST A PROLIFERATING INDUCING LIGAND (APRIL) |
摘要 |
PROBLEM TO BE SOLVED: To provide compositions of anti-APRIL specific antibodies and methods to use such antibodies in modulating the biological activity APRIL, particularly in inflammatory diseases, inhibition of cell proliferation and cancer.SOLUTION: The present invention relates to a binding compound which binds to human APRIL, the compound binding to APRIL of the amino acid sequence IRSMPSHPDRA or VSREGQGRQ. |
申请公布号 |
JP2015164956(A) |
申请公布日期 |
2015.09.17 |
申请号 |
JP20150117304 |
申请日期 |
2015.06.10 |
申请人 |
BIONOVION HOLDING BV |
发明人 |
JAN PAUL MEDEMA;HANS VAN EENENNAAM;MARCO GUADAGNOLI;FIONA CLARE KIMBERLEY;UYEN TRUONG PHAN |
分类号 |
C07K16/18;A61K39/395;A61P29/00;A61P35/00;A61P37/02;A61P37/04;A61P37/06;A61P43/00 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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