摘要 |
<p>A process for the preparation ofβ,γ-unsaturated-γ,γ-disubstituted esters 1 with high E/Z- andβ,γ/α,β-ratios, Formula (1) by reacting at a temperature of between about 130 and 170 degrees centigrade the conjugated malonate Formula (3) with, a group I, II or III metal halide or an organic cation/halide anion pair, an inorganic proton source and a polar solvent.</p> |