| 发明名称 | Pharmaceutical composition | ||
| 摘要 | The invention concerns a co-processed additive for a solid-dose pharmaceutical composition, the additive comprising from about 50% to 99.5% by weight of at least one pharmaceutical compression aid and from about 0.5% to 50% by weight of at least one pharmaceutical lubricant, the melting point of said compression aid(s) being higher than the melting point of said lubricant(s). The co-processed additive may be in the form of a physically bound composite whereby the lubricant is associated with the surface of the compression aid particles. | ||
| 申请公布号 | US9119790(B2) | 申请公布日期 | 2015.09.01 |
| 申请号 | US201013498528 | 申请日期 | 2010.09.24 |
| 申请人 | ZENBURY INTERNATIONAL LIMITED | 发明人 | Crowley Michael;Gage Amanda;Maegli Jack;O'Reilly Timothy |
| 分类号 | A61K47/26;A61K47/36;A61K47/04;A61K47/38;A61K9/20;A61K9/16 | 主分类号 | A61K47/26 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A co-processed additive for a solid-dose pharmaceutical composition, the additive comprising from about 50% to 99.5% by weight of at least one pharmaceutical compression aid and from about 0.5% to 50% by weight of at least one pharmaceutical lubricant, the melting point of said compression aid(s) being higher than the melting point of said lubricant(s); wherein the additive is in the form of a physically bound composite of the compression aid and lubricant, the lubricant being associated with the outer surface of the compression aid such that no free lubricant is required prior to tableting, encapsulation or pelleting when the co-processed additive is incorporated in the solid-dose pharmaceutical composition, and wherein the lubricant is not magnesium stearate. | ||
| 地址 | Tralee IE | ||