发明名称 |
New derivatives of (Z)-1,2-diphenylethan |
摘要 |
The present invention relates to the new chemical compounds containing (Z)-1,2-diphenylethene moiety in the structures, particularly the new derivatives of cis-stilbene, the new derivatives of 4,5-diphenyl-1,3-oxazole, the new derivatives of 1-methyl-4,5-diphenyl-1H-imidazole and pharmaceutically acceptable salts thereof. The invention relates also to the application of aforementioned compounds as a microtubule-interfering agents (MIAs). The new derivatives, because of their potential antimitotic and antiangio-genic activity, can be used as ingredients in the preparations used in the treatment of cancer. |
申请公布号 |
PL220039(B1) |
申请公布日期 |
2015.08.31 |
申请号 |
PL20120398659 |
申请日期 |
2012.03.29 |
申请人 |
UNIWERSYTET MEDYCZNY IM. KAROLA MARCINKOWSKIEGO WPOZNANIU |
发明人 |
STEFA&Nacute,SKI TOMASZ;RÓ&Zdot,A&Nacute,SKI JAKUB |
分类号 |
C07C43/205;C07C59/64;C07C321/28;C07D233/58;C07D263/32 |
主分类号 |
C07C43/205 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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