Cd37-binding molecules and immunoconjugates thereof

摘要

Discloses the use of a purified humanized antibody or antigen-binding fragment thereof that specifically binds to CD37 in the preparation of a medicament for treating a patient having an autoimmune or inflammatory disease, wherein said humanized antibody or fragment thereof retains the ability of at least its chimeric or murine parent antibody to induce apoptosis in vitro in the absence of a cross-linking agent.