发明名称 |
Substituted bisphenyl butanoic acid derivatives as NEP inhibitors with improved in vivo efficacy |
摘要 |
<p>The present invention provides a compound of formula (I); or a pharmaceutically acceptable salt thereof, wherein X is defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of the compounds of the invention and a combination of pharmacologically active agents and a compound of the invention.</p> |
申请公布号 |
AU2014216417(A1) |
申请公布日期 |
2015.08.27 |
申请号 |
AU20140216417 |
申请日期 |
2014.02.12 |
申请人 |
NOVARTIS AG |
发明人 |
BARNES, DAVID WENINGER;RIGEL, DEAN FRANKLIN |
分类号 |
C07D271/113;A61K31/4245;A61P9/00;A61P11/00;A61P13/00;A61P25/00;A61P29/00 |
主分类号 |
C07D271/113 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|