| 摘要 |
FIELD: medicine.SUBSTANCE: claimed group of inventions relates to field of medicine. Claimed methods of prevention, treatment or reversion of symptoms of pulmonary fibrous disease in subject, which include introduction to subject of isolated antibody against lysyloxidase-like protein 2 (LOXL), which specifically binds with protein LOXL2 and/or inhibits activity of LOXL2 protein, thereby preventing, curing or inducing reversion of symptoms of pulmonary fibrous, where symptom is increase of number of leucocytes in subject's lungs. Claimed is pharmaceutical composition, which contains isolated anti-LOXL2 antibody and pharmaceutically acceptable filler.EFFECT: group of inventions provides effective means and methods for prevention, treatment or reversion of symptoms of pulmonary fibrous disease in subject.9 cl, 19 dwg, 2 tbl, 3 ex |
