| 主权项 |
1. A compound of formula (I) or a pharmaceutically acceptable salt, solvate or polymorph thereof, wherein R1 is hydrogen, fluorine, hydroxyl, amine, C1-6 alkyl, C1-6alkylamino, C1-6 alkoxy, C3-7 cycloalkyl, C4-7 heterocycle, aryl, bicyclic heterocycle, arylalkyl, heteroaryl, heteroarylalkyl, aryloxy, heteroaryloxy, carboxylic acid, carboxylic ester, carboxylic amide each of which is optionally substituted by one or more substituents independently selected from halogen, hydroxyl, amino, C1-6 alkyl, di-(C1-6)alkylamino, (C1-4)alkoxy-(C1-4)alkyl, C1-6 alkylamino, C1-6 alkyl, C1-6alkoxy, C3-6 cycloalkyl, carboxylic acid, carboxylic ester, carboxylic amide, heterocycle, aryl, alkenyl, alkynyl, arylalkyl, heteroaryl, heteroarylalkyl, or nitrile, R2 is C1-6 alkyl, each of which is optionally substituted by one or more substituents independently selected from halogen, hydroxyl, amino, nitrile, carboxylic acid, carboxylic ester, carboxylic amide, C1-3 alkyl, C1-3alkoxy or C3-6 cycloalkyl, sulfone, sulfoxide, or nitrile, with the proviso that N-(2-amino-5-phenethylpyrimidine-4-yl)-N-pentylamine is excluded. |
