发明名称 |
Compositions that reversibly gel and de-gel |
摘要 |
A modified or isolated composition comprising a gel. The gel includes a plurality of first polymers, each of said first polymers having first functional groups comprising a first nucleic acid sequence attached as side-chains thereto. The gel includes a plurality of second polymers, each of said second polymers having second functional groups comprising a second nucleic acid sequence attached as side-chains thereto, said first and said second functional groups forming a reversible cross-link between said first and said second polymers, wherein said cross-link comprises a plurality of hydrogen bonds between complementary base portions of said first and said second nucleic acid sequences. |
申请公布号 |
US9114189(B2) |
申请公布日期 |
2015.08.25 |
申请号 |
US201012725065 |
申请日期 |
2010.03.16 |
申请人 |
Alcatel Lucent |
发明人 |
Mills, Jr. Allen P.;Yurke Bernard |
分类号 |
C07H21/04;A61L27/26;C12Q1/68;A61L27/52;C08F265/04;C08F283/00;C08F289/00;C08L51/00 |
主分类号 |
C07H21/04 |
代理机构 |
Hitt Gaines, P.C. |
代理人 |
Hitt Gaines, P.C. |
主权项 |
1. A modified or isolated composition, comprising:
a gel including:
a plurality of first polymers, each of said first polymers having first functional groups comprising a first nucleic acid sequence attached as side-chains thereto; anda plurality of second polymers, each of said second polymers having second functional groups comprising a second nucleic acid sequence attached as side-chains thereto, said first and said second functional groups forming a reversible cross-link between said first and said second polymers, wherein said cross-link comprises a plurality of hydrogen bonds between complementary base portions of said first and said second nucleic acid sequences. |
地址 |
Boulogne-Billancourt FR |