发明名称 Administration of gamma hydroxybutyrate with monocarboxylate transporters
摘要 <p>One embodiment of the present invention is to improve the safety and efficacy of the administration of GHB or a salt thereof to a patient. It has been discovered that the concomitant administration of an MCT inhibitor, such as diclofenac, valproate, or ibuprofen, will affect GHB administration. For example, it has been discovered that diclofenac lowers the effect of GHB in the body, thereby potentially causing an unsafe condition. Furthermore, it has been discovered that valproate increases the effect of GHB on the body, thereby potentially causing an unsafe condition.</p>
申请公布号 AU2014223373(A1) 申请公布日期 2015.08.20
申请号 AU20140223373 申请日期 2014.02.28
申请人 JAZZ PHARMACEUTICALS IRELAND INSTITUTE 发明人 ELLER, MARK
分类号 A61K31/19;A61K31/196;A61P11/00;A61P25/20;A61P43/00 主分类号 A61K31/19
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