摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: disclosed are pharmaceutical antibacterial composition and methods of treatment or prevention of bacterial infections by its application or by application of combination of its ingredients (versions). Pharmaceutical composition contains pharmaceutically effective quantity of: (a) sulbactam or its pharmaceutically acceptable salt and (b) beta-lactamase inhibitor trans-7-oxo-6-(sulphoxy)-1,6-diazabicyclo-[3.2.1]-octane-2-carboxamide or its pharmaceutically acceptable salt.EFFECT: increase of antibacterial activity of claimed combination (synergism) against strains, which produce beta-lactamases of extended spectrum.15 cl, 1 tbl |