| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine and concerns a pharmaceutical composition in the form of a film-coated tablet. As an active substance, the composition contains moxifloxacin hydrochloride in a therapeutically effective amount, and auxiliary ingredients, i.e. silicon dioxide, sodium croscarmellose, an excipient and a lubricant, but it is free from lactose. The excipient represents microcrystalline cellulose or its combination with magnesium carbonate basic. A method for producing the composition involves mixing powders of moxifloxacin hydrochloride, excipient, silicon dioxide, moisturising, granulating, drying, lubricating, tabletting and coating.EFFECT: preparation is applicable to control bacterial infections and possesses stability, adequate strength, good appearance and high release rate.7 cl, 1 tbl, 6 ex |
