Disclosed herein are methods for monitoring expression of C9ORF72 mRNA and protein in an animal with C9ORF72 specific inhibitors. Such C9ORF72 specific inhibitors include antisense compounds.
申请公布号
EP2906697(A1)
申请公布日期
2015.08.19
申请号
EP20130847099
申请日期
2013.10.15
申请人
ISIS PHARMACEUTICALS, INC.;THE JOHNS HOPKINS UNIVERSITY
发明人
BENNETT, C. FRANK;FREIER, SUSAN M.;ROTHSTEIN, JEFFREY D.;DONNELLY, CHRISTOPHER;SATTLER, RITA, G.