摘要 |
PROBLEM TO BE SOLVED: To provide a compound which can be used for &sgr;1 receptor agonist having N-methyl-D-aspartate antagonist activity.SOLUTION: This invention provides a morphinan compound represented by formula (I) or pharmacologically acceptable salt thereof, where Ris CHor CD; Ris CH, CHD, CHDor CD, where at least one deuterium atom is present at Ror R. |