发明名称 MORPHINAN COMPOUNDS
摘要 PROBLEM TO BE SOLVED: To provide a compound which can be used for &sgr;1 receptor agonist having N-methyl-D-aspartate antagonist activity.SOLUTION: This invention provides a morphinan compound represented by formula (I) or pharmacologically acceptable salt thereof, where Ris CHor CD; Ris CH, CHD, CHDor CD, where at least one deuterium atom is present at Ror R.
申请公布号 JP2015145407(A) 申请公布日期 2015.08.13
申请号 JP20150078415 申请日期 2015.04.07
申请人 CONCERT PHARMACEUTICALS INC 发明人 PHILIP B GRAHAM;I ROBERT SILVERMAN
分类号 C07D221/28;A61K31/195;A61K31/485;A61K31/49;A61K45/00;A61P9/00;A61P11/00;A61P17/00;A61P19/08;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P27/06;A61P27/16;A61P29/00;A61P35/00;A61P43/00 主分类号 C07D221/28
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