摘要 |
Solid phase extraction (SPE) disks provide the greatest extraction efficiency when the maximum surface area of the disk is exposed to the sample. Such may be accomplished with the present disclosure wherein an SPE disk is secured within a cavity of a disk holder apparatus such that the SPE disk compresses against a side wall defining the cavity and forms a seal therebetween. The disk holder apparatus may be used in an open design for vacuum applications, or in a sealed design with a closure, when using positive pressure to force the sample through the disk. Examples of various configurations for the disk holder apparatus and methods of use are provided. |