| 发明名称 |
TREATING DISEASES BY MODULATING A SPECIFIC ISOFORM OF MKL1 |
| 摘要 |
The present invention relates to a method for treating a disease in a subject by modulating an isoform of MKL-1 by administering to said subject a therapeutically effective amount of a modulator of said isoform of MKL1, wherein said isoform of MKL1 comprises the amino acid sequence of SEQ ID NO:1. |
| 申请公布号 |
US2015218238(A1) |
申请公布日期 |
2015.08.06 |
| 申请号 |
US201314406057 |
申请日期 |
2013.06.28 |
| 申请人 |
NOVARTIS FORSCHUNGSSTIFTUNG, ZWEIGNIEDERLASSUNG FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEAR |
发明人 |
Chiquet-Ehrismann Ruth;Sack Ragna;Scharenberg Matthias A. |
| 分类号 |
C07K14/47;G01N33/68;G01N33/574;A61K31/713;C07K16/18 |
主分类号 |
C07K14/47 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating a disease in a subject by modulating an isoform of MKL-1 by administering to said subject a therapeutically effective amount of a modulator of said isoform of MKL1, wherein said isoform of MKL1 comprises the amino acid sequence of SEQ ID NO:1. |
| 地址 |
Basel CH |
