Rotas de síntese para 2(s), 4(s), 5(s), 7(s) - 2, 7 dialquil-4-hidroxi-2-amino-8-aril-octanoil amida

摘要

The invention relates to a process for the preparation of compounds that are important building blocks in convergent synthesis routes to 2(S),4(S),5(S),7(S)-2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amides or pharmaceutically acceptable salts thereof, such as the compound Aliskiren, and to a process for the preparation of these octanoyl amides, comprising reacting said building block.