主权项 |
1. A method for prognosis of cancer in a subject, said method comprising:
a) contacting a sample suspected (CTCs) from a subject with a reagent specific for a first cell marker and a reagent specific for a second cell marker, wherein said first and second cell marker independently selectively bind to said CTCs; b) analyzing said circulating tumor cells (CTCs) of said sample by detecting said reagent specific for said first cell marker and said reagent for said second cell marker; and c) calculating a ratio of said first cell marker to said second cell marker in the sample, wherein a higher ratio indicates a negative prognostic indicator and predicts a poor response to therapy. |