发明名称 METHOD FOR CATEGORIZING CIRCULATING TUMOR CELLS
摘要 The present invention provides method for categorizing circulating tumor cells (CTCs) using various cellular markers and revealing or non-revealing assays which provide beneficial insights for clinical staging and therapy decision making in cancer patients.
申请公布号 US2015212091(A1) 申请公布日期 2015.07.30
申请号 US201514678415 申请日期 2015.04.03
申请人 Kuhn Peter 发明人 Kuhn Peter
分类号 G01N33/574 主分类号 G01N33/574
代理机构 代理人
主权项 1. A method for prognosis of cancer in a subject, said method comprising: a) contacting a sample suspected (CTCs) from a subject with a reagent specific for a first cell marker and a reagent specific for a second cell marker, wherein said first and second cell marker independently selectively bind to said CTCs; b) analyzing said circulating tumor cells (CTCs) of said sample by detecting said reagent specific for said first cell marker and said reagent for said second cell marker; and c) calculating a ratio of said first cell marker to said second cell marker in the sample, wherein a higher ratio indicates a negative prognostic indicator and predicts a poor response to therapy.
地址 Solana Beach CA US