| 发明名称 | Crystalline microspheres and the process of manufacturing the same | ||
| 摘要 | The present invention relates to microspheres comprising a core material, wherein the microsphere is perfectly spherical and has a moisture content less than 1%, and the method of manufacturing the same. The present invention is useful in the manufacture of sustained and modified release active pharmaceutical ingredient (API) microspheres, as a free flowing excipient for mini-tablets and in the manufacture of API dispersions. | ||
| 申请公布号 | US9089487(B2) | 申请公布日期 | 2015.07.28 |
| 申请号 | US201313870556 | 申请日期 | 2013.04.25 |
| 申请人 | SPI Pharma, Inc. | 发明人 | Propst Cecil W.;Meadows Marc W.;Todd Michael S. |
| 分类号 | A61K9/16 | 主分类号 | A61K9/16 |
| 代理机构 | Morgan, Lewis & Bockius LLP | 代理人 | Morgan, Lewis & Bockius LLP |
| 主权项 | 1. A microsphere comprising a core material, wherein the microsphere has a circularity greater than 0.95, an aspect ratio greater than 0.95, and lacks porosity. | ||
| 地址 | Wilmington DE US | ||