摘要 |
FIELD: medicine.SUBSTANCE: invention refers to biology and medicine, and can be used in clinical practice for therapy of diseases related to lipid storage disease and disorders of lipoprotein metabolism. What is presented is a sorbent for removal lipoproteins (LDLP) from human plasma and blood, which contains a non-woven microfiber matrix of polypropylene and polyacrylic acid covalently bond to a matrix surface. The sorbent is produced by photo-induced graft polymerisation of acrylic acid on the surface of the sorbent matrix. The sorbent matrix is processed with a photoinitiator solution in a volatile solvent and air-dried. The sorbent matrix is then immersed into an aqueous solution of acrylic acid, removed from a solution of acrylic acid, laid on a flat substrate, coated with an ultraviolet-transparent plate from above and exposed to ultraviolet through this plate. The produced sorbent has the high sorptive capacity and LDLP selectivity.EFFECT: method is easy to implement and cost-effective.2 cl, 1 tbl, 1 ex |