TUMOR-SPECIFC GM-CSF CYTOKINE RESPONSE AS PREDICTOR OF CANCER VACCINE EFFECTIVENESS
摘要
The present invention relates to methods of treating cancer with a cancer vaccine using granulocyte-macrophage colony-stimulating factor (GM-CSF) as a biomarker; methods of prognosticating an outcome of cancer treatment with a cancer vaccine using GM-CSF as a biomarker; methods for qualifying subjects for cancer vaccination using GM-CSF as a biomarker; methods for comparing the efficacy of two or more cancer vaccine treatments based on GM-CSF response; and kits for the effective treatment of cancer.
申请公布号
EP2788025(A4)
申请公布日期
2015.07.22
申请号
EP20120855305
申请日期
2012.12.07
申请人
BIOVEST INTERNATIONAL, INC.;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人
WILSON, WYNDHAM, H.;SANTOS, CARLOS;KWAK, LARRY, W.;NEELAPU, SATTVA S.